Growth factor therapy and autologous lymph node transfer in lymphedema.
Identifieur interne : 004E57 ( Main/Exploration ); précédent : 004E56; suivant : 004E58Growth factor therapy and autologous lymph node transfer in lymphedema.
Auteurs : Markku L Hteenvuo [Finlande] ; Krista Honkonen ; Tomi Tervala ; Tuomas Tammela ; Erkki Suominen ; Johanna L Hteenvuo ; Ivana Kholová ; Kari Alitalo [Finlande] ; Seppo Yl Herttuala ; Anne SaaristoSource :
- Circulation [ 1524-4539 ] ; 2011.
Descripteurs français
- KwdFr :
- Adénovirus humains, Animaux, Facteur de croissance endothéliale vasculaire de type C (génétique), Facteur de croissance endothéliale vasculaire de type D (génétique), Lymphoedème (), Lymphoedème (anatomopathologie), Modèles animaux de maladie humaine, Noeuds lymphatiques (transplantation), Suidae, Sérome (), Thérapie génétique (), Vecteurs génétiques, beta-Galactosidase (génétique).
- MESH :
- anatomopathologie : Lymphoedème.
- génétique : Facteur de croissance endothéliale vasculaire de type C, Facteur de croissance endothéliale vasculaire de type D, beta-Galactosidase.
- Adénovirus humains, Animaux, Lymphoedème, Modèles animaux de maladie humaine, Noeuds lymphatiques, Suidae, Sérome, Thérapie génétique, Vecteurs génétiques.
English descriptors
- KwdEn :
- Adenoviruses, Human, Animals, Disease Models, Animal, Genetic Therapy (methods), Genetic Vectors, Lymph Nodes (transplantation), Lymphedema (pathology), Lymphedema (surgery), Lymphedema (therapy), Seroma (therapy), Swine, Vascular Endothelial Growth Factor C (genetics), Vascular Endothelial Growth Factor D (genetics), beta-Galactosidase (genetics).
- MESH :
- chemical , genetics : Vascular Endothelial Growth Factor C, Vascular Endothelial Growth Factor D, beta-Galactosidase.
- methods : Genetic Therapy.
- pathology : Lymphedema.
- surgery : Lymphedema.
- therapy : Lymphedema, Seroma.
- transplantation : Lymph Nodes.
- Adenoviruses, Human, Animals, Disease Models, Animal, Genetic Vectors, Swine.
Abstract
Lymphedema after surgery, infection, or radiation therapy is a common and often incurable problem. Application of lymphangiogenic growth factors has been shown to induce lymphangiogenesis and to reduce tissue edema. The therapeutic effect of autologous lymph node transfer combined with adenoviral growth factor expression was evaluated in a newly established porcine model of limb lymphedema.
DOI: 10.1161/CIRCULATIONAHA.110.965384
PubMed: 21282502
Affiliations:
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Le document en format XML
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first="Tuomas" last="Tammela">Tuomas Tammela</name></author><author><name sortKey="Suominen, Erkki" sort="Suominen, Erkki" uniqKey="Suominen E" first="Erkki" last="Suominen">Erkki Suominen</name></author><author><name sortKey="L Hteenvuo, Johanna" sort="L Hteenvuo, Johanna" uniqKey="L Hteenvuo J" first="Johanna" last="L Hteenvuo">Johanna L Hteenvuo</name></author><author><name sortKey="Kholova, Ivana" sort="Kholova, Ivana" uniqKey="Kholova I" first="Ivana" last="Kholová">Ivana Kholová</name></author><author><name sortKey="Alitalo, Kari" sort="Alitalo, Kari" uniqKey="Alitalo K" first="Kari" last="Alitalo">Kari Alitalo</name><affiliation><country>Finlande</country><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName><orgName type="university">Université d'Helsinki</orgName></affiliation></author><author><name sortKey="Yl Herttuala, Seppo" sort="Yl Herttuala, Seppo" uniqKey="Yl Herttuala S" first="Seppo" last="Yl 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Honkonen</name></author><author><name sortKey="Tervala, Tomi" sort="Tervala, Tomi" uniqKey="Tervala T" first="Tomi" last="Tervala">Tomi Tervala</name></author><author><name sortKey="Tammela, Tuomas" sort="Tammela, Tuomas" uniqKey="Tammela T" first="Tuomas" last="Tammela">Tuomas Tammela</name></author><author><name sortKey="Suominen, Erkki" sort="Suominen, Erkki" uniqKey="Suominen E" first="Erkki" last="Suominen">Erkki Suominen</name></author><author><name sortKey="L Hteenvuo, Johanna" sort="L Hteenvuo, Johanna" uniqKey="L Hteenvuo J" first="Johanna" last="L Hteenvuo">Johanna L Hteenvuo</name></author><author><name sortKey="Kholova, Ivana" sort="Kholova, Ivana" uniqKey="Kholova I" first="Ivana" last="Kholová">Ivana Kholová</name></author><author><name sortKey="Alitalo, Kari" sort="Alitalo, Kari" uniqKey="Alitalo K" first="Kari" last="Alitalo">Kari Alitalo</name><affiliation><country>Finlande</country><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName><orgName type="university">Université d'Helsinki</orgName></affiliation></author><author><name sortKey="Yl Herttuala, Seppo" sort="Yl Herttuala, Seppo" uniqKey="Yl Herttuala S" first="Seppo" last="Yl Herttuala">Seppo Yl Herttuala</name></author><author><name sortKey="Saaristo, Anne" sort="Saaristo, Anne" uniqKey="Saaristo A" first="Anne" last="Saaristo">Anne Saaristo</name></author></analytic><series><title level="j">Circulation</title><idno type="eISSN">1524-4539</idno><imprint><date when="2011" type="published">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenoviruses, Human</term><term>Animals</term><term>Disease Models, Animal</term><term>Genetic Therapy (methods)</term><term>Genetic Vectors</term><term>Lymph Nodes (transplantation)</term><term>Lymphedema (pathology)</term><term>Lymphedema (surgery)</term><term>Lymphedema (therapy)</term><term>Seroma (therapy)</term><term>Swine</term><term>Vascular Endothelial Growth Factor C (genetics)</term><term>Vascular Endothelial Growth Factor D (genetics)</term><term>beta-Galactosidase (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adénovirus humains</term><term>Animaux</term><term>Facteur de croissance endothéliale vasculaire de type C (génétique)</term><term>Facteur de croissance endothéliale vasculaire de type D (génétique)</term><term>Lymphoedème ()</term><term>Lymphoedème (anatomopathologie)</term><term>Modèles animaux de maladie humaine</term><term>Noeuds lymphatiques (transplantation)</term><term>Suidae</term><term>Sérome ()</term><term>Thérapie génétique ()</term><term>Vecteurs génétiques</term><term>beta-Galactosidase (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Vascular Endothelial Growth Factor C</term><term>Vascular Endothelial Growth Factor D</term><term>beta-Galactosidase</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Lymphoedème</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Facteur de croissance endothéliale vasculaire de type C</term><term>Facteur de croissance endothéliale vasculaire de type D</term><term>beta-Galactosidase</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Genetic Therapy</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lymphedema</term><term>Seroma</term></keywords><keywords scheme="MESH" qualifier="transplantation" xml:lang="en"><term>Lymph Nodes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adenoviruses, Human</term><term>Animals</term><term>Disease Models, Animal</term><term>Genetic Vectors</term><term>Swine</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adénovirus humains</term><term>Animaux</term><term>Lymphoedème</term><term>Modèles animaux de maladie humaine</term><term>Noeuds lymphatiques</term><term>Suidae</term><term>Sérome</term><term>Thérapie génétique</term><term>Vecteurs génétiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lymphedema after surgery, infection, or radiation therapy is a common and often incurable problem. Application of lymphangiogenic growth factors has been shown to induce lymphangiogenesis and to reduce tissue edema. The therapeutic effect of autologous lymph node transfer combined with adenoviral growth factor expression was evaluated in a newly established porcine model of limb lymphedema.</div></front></TEI><affiliations><list><country><li>Finlande</li></country><region><li>Uusimaa</li></region><settlement><li>Helsinki</li></settlement><orgName><li>Université d'Helsinki</li></orgName></list><tree><noCountry><name sortKey="Honkonen, Krista" sort="Honkonen, Krista" uniqKey="Honkonen K" first="Krista" last="Honkonen">Krista Honkonen</name><name sortKey="Kholova, Ivana" sort="Kholova, Ivana" uniqKey="Kholova I" first="Ivana" last="Kholová">Ivana Kholová</name><name sortKey="L Hteenvuo, Johanna" sort="L Hteenvuo, Johanna" uniqKey="L Hteenvuo J" first="Johanna" last="L Hteenvuo">Johanna L Hteenvuo</name><name sortKey="Saaristo, Anne" sort="Saaristo, Anne" uniqKey="Saaristo A" first="Anne" last="Saaristo">Anne Saaristo</name><name sortKey="Suominen, Erkki" sort="Suominen, Erkki" uniqKey="Suominen E" first="Erkki" last="Suominen">Erkki Suominen</name><name sortKey="Tammela, Tuomas" sort="Tammela, Tuomas" uniqKey="Tammela T" first="Tuomas" last="Tammela">Tuomas Tammela</name><name sortKey="Tervala, Tomi" sort="Tervala, Tomi" uniqKey="Tervala T" first="Tomi" last="Tervala">Tomi Tervala</name><name sortKey="Yl Herttuala, Seppo" sort="Yl Herttuala, Seppo" uniqKey="Yl Herttuala S" first="Seppo" last="Yl Herttuala">Seppo Yl Herttuala</name></noCountry><country name="Finlande"><noRegion><name sortKey="L Hteenvuo, Markku" sort="L Hteenvuo, Markku" uniqKey="L Hteenvuo M" first="Markku" last="L Hteenvuo">Markku L Hteenvuo</name></noRegion><name sortKey="Alitalo, Kari" sort="Alitalo, Kari" uniqKey="Alitalo K" first="Kari" last="Alitalo">Kari Alitalo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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